vertebrates of cells: a general model and comparative analysis of Explaining differences in the lifespan and replicative capacity
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Supplementary data tml http://rspb.royalsocietypublishing.org/content/suppl/2012/07/13/rspb.2012.1129.DC1.h "Data Supplement" References ml#ref-list-1 http://rspb.royalsocietypublishing.org/content/early/2012/07/13/rspb.2012.1129.full.ht This article cites 38 articles, 10 of which can be accessed free P<P Published online 18 July 2012 in advance of the print journal. Subject collections (32 articles) theoretical biology (31 articles) physiology (36 articles) cellular biology Articles on similar topics can be found in the following collections
منابع مشابه
Explaining differences in the lifespan and replicative capacity of cells: a general model and comparative analysis of vertebrates.
A better understanding of the factors that govern individual cell lifespan and the replicative capacity of cells (i.e. Hayflick's limit) is important for addressing disease progression and ageing. Estimates of cell lifespan in vivo and the replicative capacity of cell lines in culture vary substantially both within and across species, but the underlying reasons for this variability remain uncle...
متن کاملGenetics of proliferative aging.
Human lifespan is limited by aging of both mitotic and post-mitotic cells. These two forms of aging may occur by distinct or overlapping mechanisms. Telomere erosion has been shown to limit the proliferative lifespan of human somatic cells. Other vertebrates, such as mice, possess robust telomerase activity in most cell types and their somatic cells display finite replicative lifespans as a con...
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Introduction: Endothelial progenitor colony forming unit-endothelial cells (CFU-EC) were first believed to be the progenitors of endothelial cells, named endothelial progenitor cells. Further studies revealed that they are monocytes regulating vasculogenesis. The main hindrance of these cells for therapeutic purposes is their low frequency and limited replicative potentials. This study was unde...
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Background: Somatic cell nuclear transfer (SCNT) provides an appealing alternative for the conservation and improvement of genetic material of unique and endangered species. An important prerequisite for successful SCNT is the availability of good quality donor cells, as normal embryo development is dependent upon proper reprogramming of the donor genome so that embryonic genes can be appropria...
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Microbial cells have been successfully used as biosorbents to remove heavy metals from wastewater. In some cases, dead cells appear to offer more advantages than living cells in the removal and recovery of heavy metal ions from industrial wastewater. Maintaining higher biosorption capability and understanding t...
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تاریخ انتشار 2012